| Phenol metabolic fingerprint and selection of intake biomarkers after acute and sustained consumption of red-fleshed apple versus common apple in humans. The AppleCOR study |
2022 |
Macià, Alba; Romero, Maria Paz; Yuste, Silvia; Ludwig, Iziar; Pedret, Anna; Valls, Rosa Maria; Salamanca, Patricia; Solà, Rosa; Motilva, Maria José; Rubió, Laura |
Article d'investigació |
| Variation in the Methylation of Caffeoylquinic Acids and Urinary Excretion of 3′-methoxycinnamic acid-4′-Sulfate After Apple Consumption by Volunteers |
2021 |
Rubió, Laura; Romero, Maria Paz ; Solà, Rosa; Motilva, Maria José; Clifford, Michael N. ; Macià, Alba |
Article d'investigació |
| Thermal and non-thermal processing of red-fleshed apple: how are (poly)phenol composition and bioavailability affected? |
2020 |
Yuste, Silvia; Macià, Alba; Motilva, María José; Prieto Diez, Neus; Romero, María Paz; Pedret, Anna; Solà, Rosa; Ludwig, Iziar A.; Rubió, Laura |
Article d'investigació |
| Application of Dried Blood Spot Cards combined with liquid chromatography-tandem mass spectrometry to determine eight fat-soluble micronutrients in human blood |
2020 |
Laura Rubió; Silvia Yuste; Iziar Ludwig; Maria-Paz Romero; Maria-José Motilva; Lorena Calderón; Laura Pla-Pagà; Judit Companys; Alba Macià |
Article d'investigació |
| In vivo biotransformation of (poly)phenols and anthocyanins of red-fleshed apple and identification of intake biomarkers |
2019 |
Yuste, Silvia; Ludwig, Iziar; Rubió, Laura; Romero, Mari Paz; Pedret, Anna; Valls, Rosa Maria; Solà, Rosa; Motilva, Maria José; Macià, Alba |
Article d'investigació |
| Endothelial cells deconjugate resveratrol metabolites to free resveratrol: a possible role in tissue factor modulation. |
2019 |
Fernández-Castillejo, S.; Macià, A.; Motilva, MJ.; Catalán, S.; Solà, R. |
Article d'investigació |
| Seasonal Variability of Phytochemical Composition of New Red-Fleshed Apple Varieties Compared with Traditional and New White-Fleshed Varieties. |
2018 |
Bars-Cortina D; Macià A; Iglesias I; Garanto X; Badiella L; Motilva MJ. |
Article d'investigació |
| Validation of dried blood spot cards to determine apple phenolic metabolites in human blood and plasma after an acute intake of red-fleshed apple snack. |
2018 |
Yuste, S.; Macià, A.; Ludwig, I.; Romero, M-P.; Fernández-Castillejo, S.; Catalán, U.; Motilva, M.-J.; Rubió, L. |
Article d'investigació |
| Cardiovascular benefits of phenol-enriched virgin olive oils: Insights from the virgin olive oil and HDL functionality (VOHF) study. |
2018 |
Pedret, A.; Fernández-Castillejo, S.; Valls, R-M.; Catalán, U.; Rubió, L.; Romeu, M.; Macià, A.; López de las Mazas, M-C.; Farràs, M.; Giralt, M.; Martín-Peláez,S.; Remaley, A.; Covas, M-I.; Fitó, M.; |
Article d'investigació |
| Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells. |
2018 |
López de las Hazas, M.C.; Godinho-Pereira, J.; Macià, A.; Almeida, A.F.; Ventura, M.R.; Motilva, M.-J.; Santos, C. |
Article d'investigació |
| Phytochemical profiles of new red-fleshed apple varieties compared with traditional and new white-fleshed varieties |
2017 |
Bars-Cortina D, Macià A, Iglesias I, Romero MP, Motilva MJ. |
Article d'investigació |
| Hydroxytyrosol and the colonic metabolites derived from virgin olive oil intake induce cell cycle arrest and apoptosis in colon cancer cells. |
2017 |
López de las Hazas, M-C.; Piñol, C.; Macià, A.; Motilva, M-J. |
Article d'investigació |
| Exploring the colonic metabolism of grape strawberry anthocyanins and their in-vitro apoptotic effects in HT-29 colon cancer cells. |
2017 |
López de las Hazas, M-C.; Mosele J.I.; Macià, A.; Ludwig I.; Motilva, M-J. |
Article d'investigació |
| Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells. |
2017 |
Perez-Ternero, C.; Werner, C.; Herrera González, M-D.; Motilva, M-J.; Böhm, M.; Alvarez de Sotomayor, M.; Laufs, U. |
Article d'investigació |
| Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against the superoxide production |
2017 |
Perez-Ternero, C.; Macià, A.; Alvarez de Sotomayor, M.; Parrado, J.; Motilva, M-J.; Herrera, M.D. |
Article d'investigació |
| Virgin olive oil enriched with its own phenolic compounds or complemented with thyme improves endothelial function: The potential role of plasmatic fat-soluble vitamins. A double blind, randomized, co |
2017 |
Valls, R-M.; Farràs, M.; Pedret, A.; Fernández-Castillejo, S.; Catalán, S.; Rubió, L.; Romeu, M.; Giralt, M.; Sáez, G.; Fitó, M.; Covas, M-I.; Motilva, MJ.; Solà, R. |
Article d'investigació |
| Differential absorption and metabolism of hydroxytyrosol and its precuersors oleuropein and secoiridoids |
2016 |
López de las Hazas MC.; Piñol C.; Macià A.; Romero MP.; Pedret A.; Solà R; Rubió L.; Motilva MJ. |
Article d'investigació |
| Polyphenol rich olive oils improve lipoprotein particle atherogenic ratios and subclasses profile: A randomized, crossover, controlled trial |
2016 |
Fernández-Castillejo S, valls RM, Castañer O, Rubió L, Catalán U, Pedret A, Macià A, Sampson ML, Covas MI, Fitó M, Motilva MJ, Remaley AT, Solà R. |
Article d'investigació |
| Application of dried blood spot cards to determine olive oil phenols (hydroxytyrosol metabolites) in human blood |
2016 |
López de las Hazas, M-C.; Macià, A.; Piñol, C; Motilva MJ. |
Article d'investigació |
| Human bioavailability and metabolism of phenolic compounds from red wine enriched with free or nano-encapsulated phenolic extract |
2016 |
Motilva, MJ.; Macià, A.; Romero M.P.; Rubió L.; Mercader M.; González- Ferrero C. |
Article d'investigació |
| Understanding of human metabolic pathways of different sub-classes of phenols from Arbutus unedo fruit after an acute intake |
2016 |
Mosele, J.; Macià, A.; Motilva, MJ. |
Article d'investigació |
| Stability and metabolism of Arbutus unedo bioactive compounds (phenolics and antioxidants) under in vitro digestion and colonic fermentation |
2016 |
Mosele, JI.; Macià, A.; Romero, MP.; Motilva, MJ. |
Article d'investigació |
| Application of in vitro gastrointestinal digestion and colonic fermentation models to pomegranate products (juice, pulp and peel extract) to study the stability and catabolism of phenolic compounds |
2015 |
Mosele, J.I.; Macià, A.; Romero, M.P.; Motilva, M.-J.; Rubió, L. |
Article d'investigació |
| Metabolic and Microbial Modulation of the Large Intestine Ecosystem by Non-Absorbed Diet Phenolic Compounds: A Review |
2015 |
Mosele JI.; Macià, A.; Motilva MJ. |
Article d'investigació |
| Effect of daily intake of pomegranate juice on fecal microbiota and feces metabolites from healthy volunteers. |
2015 |
Mosele JI.; Gosalbes M-J.; Macià A.; Rubió L.; Vázquez-Castellanos JF; Jiménez Hernández N.; Moya A.; Latorre A.; Motilva MJ. |
Article d'investigació |
| Optimization and validation of analytical methods for the simultaneous determination of antioxidants: Application to the analysis of tomato sauces |
2014 |
Motilva MJ, Macià A, Romero MP, Labrador A, Domínguez A, Peiró Ll. |
Article d'investigació |
| In vivo distribution and deconjugation of hydroxytyrosol phase II metabolites in red blood cells: A potential new target for hydroxytyrosol |
2014 |
Rubió, L.; Serra, A.; Macià, A.; Piñol, C.; Romero, M.P.; Motilva, M.J. |
Article d'investigació |
| Study of the Catabolism of Thyme Phenols Combining in Vitro Fermentation and Human Intervention |
2014 |
Mosele JI, Martín-Peláez S, Macià A, Farràs M, Valls RM, Catalán U, Motilva MJ. |
Article d'investigació |
| Faecal microbial metabolism of olive oil phenolic compounds: in-vitro and in-vivo approaches |
2014 |
Mosele J.I., Martín-Peláez S., Macià A., Farràs M., Valls R.M., Catalán U., Motilva M.J. |
Article d'investigació |
| Chapter 14: Determination of Procyanidins and Alkaloids in Cocoa and Biological Samples by Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry. |
2014 |
Macià, A.; Motilva, M.J.; Ortega, N. |
Capítol de llibre d'investigació |
| Gallic Acid Is an Active Component for the Anticarcinogenic Action of Grape Seed Procyanidins in Pancreatic Cancer Cells. |
2014 |
Cedó L.; Castell-Auví A.; Pallarès V.; Macià A.; Blay M.; Ardévol A.; Motilva M.J.; Pinent M. |
Article d'investigació |
| Impact of Various Factors on Pharmacokinetics of Bioactive Polyphenols: An Overview |
2014 |
Rubió, L.; Macià, A.; Motilva M.J. |
Article d'investigació |
| Metabolite profiling of olive oil and thyme phenols after a sustained intake of two phenol-enriched olive oils by humans: Identification of compliance markers |
2014 |
Rubió L, Farràs M, de la Torre R, Macià A, Romero MP, Valls RM, Solà R, Farré M, Fitó M, Motilva MJ. |
Article d'investigació |
| Effect of the co-occurring olive oil and thyme extracts on the phenolic bioaccesibility and bioavailability assessed by in vitro digetsion and cell models |
2014 |
Rubió L, Macià A, Castell-Auví A, Pinent M, Blay T, Ardévol A, Romero MP, Motilva MJ |
Article d'investigació |
| Application of dried spot cards as a rapid sample treatment method for determining hydroxytyrosol metabolites in human urine samples. Comparison with microelution solid-phase extraction |
2013 |
Serra A.; Rubió L.; Macià A.; Valls R.M.; Catalán U.; de la Torre R.; Motilva M.J. |
Article d'investigació |
| Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams |
2013 |
Serra A, Macià A, Rubió L, Anglés N, Ortega N, Morelló JR, Romero MP, Motilva MJ. |
Article d'investigació |
| Biomarkers of food intake and metabolite differences between plasma and red blood cell matrices; a human metabolomic profile approach. |
2013 |
Catalan U; Rodriguez MA; Ras MR; Macià A; Mallol R; Vinaixa M; Fernandez S; Valls RM; Pedret A; Griffin J; Salek R; Correig X; Motilva MJ; Solá R. |
Article d'investigació |
| Flavanol metabolites distribute in visceral adipose depots after a long-term intake of grape seed proanthocyanidin extract in rats |
2013 |
Serra, A.; Bladé, C.; Arola, L.; Macià, A.; Motilva, MJ. |
Article d'investigació |
| Analysis of food polyphenols by ultra high-performance liquid chromatography coupled to mass spectrometry: An overview |
2013 |
Motilva, M.J.; Serra, A.; Macià, A. |
Review |
| Development of a Phenol-Enriched Olive Oil with Both Its Own Phenolic Compounds and Complementary Phenols from Thyme |
2012 |
Rubio L, Motilva MJ, Macià A, Ramo T, Romero MP. |
Article d'investigació |
| Validation of determination of plasma metabolites derived from thyme bioactive compounds by improved liquid chromatography coupled to tandem mass spectrometry |
2012 |
Rubió, L.; Serra, A.; Macià, A.; Borràs, X.; Romero, M.P.; Motilva, M.J. |
Article d'investigació |
| A new hydroxytyrosol metabolite identified in human plasma: Hydroxytyrosol acetate sulphate |
2012 |
Rubió L, Macià A, Valls RM, Pedret A, Romero MP, Solá R, Motilva MJ. |
Article d'investigació |
| Synthetic Phenolic Antioxidants |
2012 |
Serra, A; Macià, A.; Estévez, M. |
Capítol de llibre d'investigació |
| Improved liquid-chromatography tandem mass spectrometry method for the determination of the bioactive dipeptides, carnosine and anserine: Application to analysis in chicken broth |
2012 |
Macià A, Motilva MJ, Romero MP, Labrador A, Domínguez A, Peiró Ll. |
Article d'investigació |
| Metabolic pathways of the colonic metabolism of flavonoids (flavonols, flavones and flavanones) and phenolic acids. |
2012 |
Serra A; Macia A; Romero MP; Reguant J; Ortega N; Motilva MJ |
Article d'investigació |
| Impact of olive oil phenolic concentration on human plasmatic phenolic metabolites |
2012 |
Rubió L, Valls R, Macià A, Pedret A, Giralt M, Romero MP, de la Torre R, Covas MI, Solá R, Motilva MJ. |
Article d'investigació |
| Distribution of procyanidins and their metabolites in rat plasma and tissues after an acute intake of hazelnut extract |
2011 |
Serra A, Macià A, Romero MP, Angles N, Morelló JR, Motilva MJ. |
Article d'investigació |
| Matrix composition effect on the digestibility of carob flour phenols by an in-vitro digestion model |
2011 |
Ortega N, Macia A, Romero MP, Reguant J, Motilva MJ. |
Article d'investigació |
| Metabolic pathways of the colonic metabolism of procyanidins (monomers and dimers) and alkaloids. |
2011 |
Serra A; Macia A; Romero MP; Angles N; Morello JR; Motilva MJ |
Article d'investigació |
| Rapid methods to determine procyanidins, anthocyanins, theobromine and caffeine in rat tissues by liquid chromatography-tandem mass spectrometry |
2011 |
Serra A, Macia A, Romero MP, Piñol C, Motilva MJ. |
Article d'investigació |
| Distribution of olive oil phenolic compounds in rat tissues after administration of a phenolic extract from olive cake |
2011 |
Serra A, Rubió L, Borrás X, Macià A, Romero MP, Motilva MJ. |
Article d'investigació |
| Bioavailability of phenols from a phenol-enriched olive oil |
2011 |
Suárez M, Valls RM, Romero MP, Macià A, Fernández S, Giralt M, Solà R, Motilva MJ. |
Article d'investigació |
| Organotypic co-culture system to study plant extract bioactivity on hepatocytes |
2010 |
Castell-Avuí A, Motilva MJ, Macià A, Torrell H, Bladé C, Pinent M, Arola L, Ardèvol A. |
Article d'investigació |
| Comparative study of ultra performance liquid chromatography-tandem mass spectrometry and high performance liquid chromatography-tandem mass spectrometry to determine procyanidins and alkaloids in coc |
2010 |
Ortega N, Romero MP, Macià A, Reguant J, Anglès N, Morello JR, Motilva MJ. |
Article d'investigació |
| Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models |
2010 |
Serra A, Macià A, Romero MP, Valls J, Bladé C, Arola Ll, Motilva MJ. |
Article d'investigació |
| Digestion stability and evaluation of the metabolism and transport of olive oil phenols in the human small-intestinal epithelial Caco-2/TC7 cell line |
2010 |
Soler A, Romero MP, Macià A, Saha S, Furniss CSM, Kroon P, Motilva MJ. |
Article d'investigació |
| Rapid analysis of procyanidins and anthocyanins in plasma by microelution SPE and ultra-HPLC |
2010 |
Martín, MP; Pantaleón, A; Rosekl, A; Soler, A:; Valls, J; Macià, A; Romero, MP; Motilva, MJ |
Article d'investigació |
| Methods for preparing phenolic extracts from olive cake for potential application as food antioxidants. |
2009 |
Suárez M, Romero MP, Ramo T, Macià A, Motilva MJ. |
Article d'investigació |
| Determination of procyanidins and their metabolites in plasma samples by improved liquid chromatography-tandem mass spectrometry. |
2009 |
Serra A; Macià A; Romero MP; Salvadó MJ; Busto M; Férnandez- Larrea J; Motilva MJ. |
Article d'investigació |
| Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass sp |
2009 |
Suárez M, Romero MP, Macià A, Valls RM, Fernández S, Solà R, Motilva MJ. |
Article d'investigació |
| Rapid Determination of Phenolic Compounds and Alkaloids of Carob Flour by Improved Liquid Chromatography Tandem Mass Spectrometry |
2009 |
Ortega N, Macià A, Romero MP, Trullols E, Morello JR, Anglès N, Motilva MJ. |
Article d'investigació |
| Effect of fat content on the digestibility and bioaccessibility of cocoa polyphenol by an in vitro digestion model |
2009 |
Ortega N, Reguant J,Romero MP, Macià A, Motilva MJ. |
Article d'investigació |
| Sensitivity enhancement for the analysis of naproxen in tap water by solid-phase extraction coupled in-line to capillary electrophoresis |
2008 |
Macia A, Borrull F, Calull M., Benavente, F., Hernández E., Sanz-Nebot V., barbosa J., Aguilar C, |
Article d'investigació |
| Improved liquid chromatography tandem mass spectrometry method for the determination of phenolic compounds in virgin olive oil |
2008 |
Suárez M, Macià A, Romero MP, Motilva MJ. |
Article d'investigació |
| Obtention and characterization of phenolic extracts from different cocoa sources |
2008 |
Ortega N., Romero MP., Macia A, Reguant J., Anglès N., Morelló JR., Motilva MJ. |
Article d'investigació |
| Capillary electrophoresis for the analysis of nonsteroidal anti-inflammatory drugs |
2007 |
Macia A, Borrull F, Calull M., Aguilar C, |
Article d'investigació |
| Analysis of nonsteroidal anti-inflammatory drugs in water samples using microemulsion electrokinetic capillary chromatography under pH-suppressed electroosmotic flow with an on-column preconcentration |
2006 |
Macia A, Borrull F, Calull M., Aguilar C, |
Article d'investigació |
| Different on-column preconcentration techniques to analyze some nonsteroidal anti-inflammatory drugs by micellar electrokinetic capillary chromatography in mineral waters |
2006 |
Macia A, Borrull F, Calull M., Aguilar C, |
Article d'investigació |
| Separation and on-column preconcentration of some nonsteroidal anti-inflammatory drugs by microemulsion electrokinetic capillary cromatography using high speed separations |
2005 |
Macia A, Borrull F, Calull M., Aguilar C, |
Article d'investigació |
| Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low ug/L concentration levels |
2004 |
Macia A, Borrull F, Aguilar C, Calull M. |
Article d'investigació |
| Determination of some acidic drugs in surface and sewage treatment plant waters by capillary electrophoresis - electrospray - mass spectrometry |
2004 |
Macia A, Borrull F, Calull M., Aguilar C, |
Article d'investigació |
| Improving sensitivity by large-volume sample stacking using the electroosmotic flow pump to analyze some nonsteroidal anti-inflammatory drugs by capillary electrophoresis in water samples |
2003 |
Macia A, Borrull F, Aguilar C, Calull M. |
Article d'investigació |